Understanding the Science

We feel it is important for horse owners to know and understand what they are putting on their​ horses as well as on their own hands. 

What's In It?
 eQure USA products are comprised of high grade, non-caustic alkaline elements. Each ingredient was hand selected for their efficiency as purification products, while still remaining non caustic, safe for human and animal use, and safe for the environment.

Having ingredients with proven direct beneficial effects on the live tissue of animals has been at the forefront of developing eQure products. For example, o ne key ingredient is a very versatile antioxidant that is often used to remove iron stains on hides during processing without damaging the hide. This solvent is safe to use and provides benefit by easily counteracting free-radicles and halting their destructive process in the body. Another aspect of formulation was included to remove the dead skin cells while still being safe for even the most sensitive of skin; this is what causes the "sudsing" effect you will notice when spraying the products.  In addition, the suds hold another purpose of lowering the interfacial tenstion to allow the liquid product to absorb much quicker and more effeciently into the surface it meets.

Why It Works
All eQure USA products are composed using the same base, which then is slightly altered in each product using a specialized formula that can better target each ailment. 

 Adenosine Monophosphate, an important ingrediant in the eQure base, is one of the four nitrogenous bases that comprises RNA as well as a key component of the energy carrying molecule ATP. In vital metabolic process, AMP (adenosine monophosphate) combines with a inorganic phosphate to form Adenosine diphosphate and then continues to combine with a third phosphate to create adenosine triphosphate. This is a key element to the body's functioning metabolic process. By enhancing the metabolic process, the oxygen in the blood cells increases tremendously thereby quickening the  healing process and disinfecting the area naturally .

WHITE LINE DISEASE
White Line Disease is an internal infection that affects the white line of the hoof of the horse. Traditionally, WLD is believed to be an external infection, however there is reason to believe that the black build up we recognize as WLD is actually a secondary infection. The secondary infection would compound the severity of the original blow out of the WL. If a disruption in the blood flow or lymph in the foot occurs, along with the effects of gravity, we could expect to see pathogens and dead cells or microorganisms left behind in the hoof capsule. It is also possible that toxin overloading in the blood or lymph would also cause us to see the “White line Disease”.

WLD is not a disease itself but the body’s reaction to something that cannot not be removed by traditional means (i.e. kidney, Liver), especially if the blood flow from the foot is interrupted by other factors (i.e. hoof imbalances). Essentially WLD is similar to an abscessing of the hoof as a result of infectious or toxic agents being trapped within the capsule. In order to relieve the pressure from the gases that build up from the decomposing matter and anaerobic bacteria, the white line pops like a balloon and releases the damaging agents which then exit the capsule through the bottom of the hoof between the non-pigmented hoof wall and the sole.

​The White Line is a condensed form of fascia and it connects the hoof wall to the sole. It is one of the weakest structures of the hoof and a continuation of the coronet band (we often see the WL blow out rather than the coronet band as the hoof has a greater ability to protect the boday from further infection than an open wound at the coronet band). It is produced by the papillae and the lamina. This fascia is not only a connective tissue but is also a transportation vessel for lymph, and nutrients. Lymph is a clear substance that is comprised primarily of interstitial fluid. This lymph is continuously changing by picking up unwanted substances such as bacteria and dead cells; and exchanges a variety of proteins and excess interstitial fluid with the blood stream. Lymph nodes act as filters for the lymphatic fluid. Once in the lymph nodes bacteria is destroyed and unused, proteins are sent back to the body through the interstitium to be used again. Lymph contains a high number of white blood cells and lymphocytes.​
Reference- Jennifer Lockert

Up until now, the most effective way to get a handle on WLD (seedy toe) was by resecting the hoof wall.

WLD is an anaerobic bacteria, which means oxygen does not need to be present for it to thrive.

eWLD works by going inside the tubules. The tubules work like a straw so the eWLD is able to attach to the bacteria, leading to elimination of the nucleus.
Nutritional factors aided by a program of treatment will also help this infection from reoccurring.
THRUSH
Thrush in horses results from bacterium that causes a degenerative infection of the central and collateral grooves of the frog. In classic cases, it results from the softening and damage to the soft tissue structures of the horse’s foot from standing in wet, dirty, and muddy conditions. Traditionally, thrush has only been thought as being linked to poor stable management, however poor foot care as well as conformation can also be linked to increased occurrence. In relation to conformation, horses with long narrow feet, contracted heels, and frog deformity are predisposed to this ailment with an even greater prevalence being found in horses with deep and narrow frog clefts. 

There are a variety of bacteria and fungi responsible for causing necrosis, however one particularly aggressive species of bacteria called fusobacterium necrophorum attacks the softened tissues of the frog, causing it to rot away. After the frog is initially infected, a secondary anaerobic bacterial infection begins in the central and collateral sulci. The affected sulci become moist and discharge a foul-smelling, black substance. Although this is a serious infection, horses often appear undisturbed by the affliction with no clear discomfort or lameness apparent in early stages. However, if the infection is left untreated it may under run the adjacent sole and spread to involve deeper structures of the hoof such as the deep digital cushion, hoof wall, and heel bulb. With a exaggerated infection a varying degree of unsoundess and discomfort may become evident.

Thrush is a common ongoing condition in hoof capsules. 

Thrush is developed from urine and feces being absorbed by the frog and sole.
Sulcus thrush is a similar yeast  bacteria and does not need to have dirty conditions to live.

eThrush clears the infection in as little as one application.

Scratches
Equine pastern dermatitis is not a single disease but rather a problematic skin condition that can be caused and perpetuated by a variety of environmental and genetic factors. There is no specific causative agent for EPD, however, consistently having wet and dirty skin on the lower legs increases a horses susceptibility due to the invasion of bacteria and fungus. EPD can range from mild to severe with the mildest form termed scratches. Scratches is distinguished by hypertrophy; the presence of dry scales and crusts and a discharge on the caudal surface of the pastern and fetlock. It is painful to horses and frustrating to owners. Mild cases are usually amenable to simple cleaning and topical treatment but there are other cases that become increasingly frustrating over time.. Uncovering the underlying causes before treatment is key to minimizing treatment failure and frustration. It is important to monitor the pastern regions of horses regularly to catch EPD in its earliest stages with indicators such as scabs and inflamed skin. Once the warning signs are detected, it is helpful to shave the affected area to allow direct topical treatment and to keep the skin dry. Once the area is clean, treatment can begin.​

The slide to your right show the application of eScratches on live scratches bacteria.​​

Top picture:
​Live scratches bacteria, sprayed with eScratches. 15 minutes post application measurments were approximately the same but there were visible changes in the internal structures of the cell.

Bottom picture:
26 minutes post application of eScratches (measured at 388.03µM). You can see a drastic change in the cell and observe the cell dying.

pH level of scratches bacteria

pH level immediately after eScratches application